WHO Issues Comprehensive Guidelines on Infertility Prevention and Treatment

Thu 11th Dec, 2025

Infertility is a condition affecting a significant portion of the global population, with the World Health Organization (WHO) estimating that approximately one in six individuals of reproductive age will experience it at some point. Defined as the inability to achieve pregnancy after 12 months of regular, unprotected intercourse, infertility poses considerable emotional, social, and financial challenges for those affected. Recognizing these burdens and the disparities in access to reproductive health services, the WHO has released new evidence-based guidelines aimed at improving prevention, diagnosis, and management of infertility worldwide.

Global Need for Improved Reproductive Care

The WHO's new recommendations come as a response to persistent gaps in infertility care, particularly in low- and middle-income countries. Many individuals and couples lack adequate access to appropriate medical support, and financial coverage for infertility treatments remains inconsistent, even in developed countries. For example, in countries like Germany, health insurance providers only partially cover the costs of fertility treatments under certain conditions. This often results in significant out-of-pocket expenses for those seeking assistance.

Beyond financial barriers, the psychosocial impacts of infertility are considerable. Individuals may face increased risks of depression, anxiety, relationship strain, and social stigma. The WHO emphasizes the importance of addressing these factors as part of comprehensive care.

Gender Disparities and Social Consequences

Despite the fact that infertility can result from factors affecting any partner, women are frequently blamed for the inability to conceive. The WHO notes that a significant proportion of women experiencing infertility also report exposure to intimate partner violence. This underscores the need for broader societal education and support to address harmful stereotypes and ensure equitable treatment for all affected individuals.

Preventable Factors and Public Health Education

The WHO guidelines highlight that some causes of infertility are preventable. These include sexually transmitted infections (STIs) such as chlamydia and gonorrhea, as well as lifestyle factors like smoking, excessive alcohol consumption, and obesity. The recommendations advocate for proactive public education, including the distribution of informational materials in schools and healthcare facilities. Such initiatives should inform individuals that fertility naturally declines with age, particularly for women, as both the quantity and quality of eggs decrease over time.

For younger women, hormonal imbalances such as those found in polycystic ovary syndrome (PCOS) can disrupt regular ovulation and contribute to infertility. Other potential causes include fallopian tube blockages or scarring from untreated infections or unsafe abortions, as well as uterine abnormalities and conditions like endometriosis.

In men, infertility can be related to a variety of causes, including complications from previous STIs, hormonal disorders, or physical issues such as varicoceles (enlarged veins in the scrotum) that impair sperm production. Assessment of male fertility typically involves semen analysis to evaluate sperm count, motility, morphology, and viability.

Recommendations for Comprehensive Care

The WHO's guidelines advocate for integrated, patient-centered approaches to infertility care. This includes ensuring access to accurate information, preventive measures, early diagnosis, and effective treatment options. The guidelines also call for addressing the psychological and social dimensions of infertility, promoting gender equity, and working to reduce stigma associated with the condition.

The new WHO recommendations represent a significant step toward standardizing infertility prevention and care globally. By emphasizing evidence-based strategies and a holistic approach, the guidelines aim to support individuals and couples in achieving their reproductive goals, regardless of geographic or socioeconomic barriers.


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