Research Indicates Pregnant Vapers Encounter Lower Toxic Exposure Than Smokers

Sun 22nd Jun, 2025

Recent research from City St George's, University of London, reveals that pregnant women who vape are exposed to significantly fewer toxic substances compared to those who smoke traditional cigarettes. This study, published in the journal Nicotine and Tobacco Research, provides essential insights into the relative safety of vaping during pregnancy.

As smoking cessation during pregnancy remains a critical health concern for both the mother and her developing fetus, an increasing number of expectant mothers are opting to vape as a potential alternative to smoking. However, prior to this research, there was a notable absence of reliable data regarding the exposure levels to harmful chemicals associated with vaping during pregnancy.

This comprehensive study is the first to thoroughly compare the exposure to toxic substances from smoking versus vaping among pregnant women. A total of 140 participants were recruited from five hospitals across the United Kingdom, divided into several groups: those who exclusively smoked (38 women), those who solely vaped after previously smoking (35 women), those who both smoked and vaped (25 women), those using nicotine replacement therapy (10 women), and a control group of non-smokers (32 women).

Researchers collected urine samples during routine antenatal appointments to measure nicotine and the presence of harmful substances. Specifically, they assessed the levels of 14 different volatile organic compounds (VOCs), known to be significant toxicants associated with both smoking and vaping. These compounds are recognized as major contributors to cancer risk, as well as respiratory and cardiovascular diseases.

The findings indicated that women who exclusively vaped exhibited significantly lower levels of 10 VOCs in their urine compared to those who exclusively smoked, with reductions ranging from 44% to 97%. Additionally, the levels of 13 VOCs were found to be comparable between the women who vaped and those who had no prior exposure to nicotine or tobacco products.

While the study highlights the reduced exposure to harmful chemicals for pregnant women who choose vaping over smoking, the lead researcher emphasized that this does not imply that vaping is entirely safe during pregnancy. The ongoing research aims to investigate whether vaping has any adverse health consequences for either the mother or the unborn child.

The study underscores the importance of continuous monitoring of vaping products, as the landscape of these products is rapidly evolving. The researchers noted that while they focused on the main known toxins at the time of the study, there may be additional harmful substances in vaping products that were not examined.

This research involved collaboration among experts from City St George's, University of London, University of Nottingham, University College London, King's College London, the US Centers for Disease Control and Prevention, and the UK Health Security Agency.


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