Study Finds No Link Between Aluminum in Childhood Vaccines and Chronic Disorders

Tue 15th Jul, 2025

A comprehensive cohort study conducted in Denmark has established that exposure to aluminum from childhood vaccines does not correlate with an increased risk of developing various chronic disorders. The research, published in the Annals of Internal Medicine, aims to address concerns surrounding the safety of aluminum-adjuvanted vaccines.

The study involved a substantial sample size of 1,224,176 children born in Denmark between 1997 and 2018. Researchers utilized the Danish national health registries to track the cumulative exposure to aluminum from vaccines administered to children before the age of two, as well as the incidence of 50 different chronic disorders.

Throughout the 24-year period of the Danish Childhood Vaccination Program, which saw the introduction of vaccines with differing aluminum content, the study aimed to investigate associations between aluminum exposure and the development of autoimmune, atopic (allergic), and neurodevelopmental disorders.

Data were collected on 36 autoimmune disorders, nine atopic or allergic disorders, and five neurodevelopmental disorders. The children were monitored from the age of two until December 31, 2020, or until they reached age five, passed away, or were lost to follow-up.

Using Cox proportional hazards regression models, the researchers calculated adjusted hazard ratios to evaluate how the risk changed with an increase in aluminum exposure. The findings indicated a hazard ratio of 0.98 for autoimmune outcomes per 1-milligram increase in aluminum exposure from childhood vaccinations, suggesting no increased risk. Similarly, the ratios were 0.99 for atopic or allergic disorders and 0.93 for neurodevelopmental disorders.

When focusing specifically on autism spectrum disorder and attention-deficit/hyperactivity disorder, the hazard ratios were 0.93 and 0.90, respectively, indicating no significant association with increased aluminum exposure.

This nationwide research contributes valuable evidence to the ongoing discussions regarding the safety of aluminum-adjuvanted vaccines, particularly concerning fears about potential neurological and chronic health risks. It underscores the importance of rigorous scientific studies in dispelling myths and ensuring public confidence in vaccination programs.


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