Innovative Tool Enhances Seizure Prediction, Optimizing EEG Resource Usage

Tue 20th May, 2025

In intensive care units across hospitals, a new scoring tool is revolutionizing the way neurologists assess the risk of brain-damaging seizures in critically ill patients. This innovative scorecard not only has the potential to save lives but also streamlines the use of expensive medical equipment.

Prior to 2019, monitoring a patient's brain activity to anticipate seizures was a cumbersome process that often required continuous EEG (cEEG) monitoring for 24 to 48 hours. These machines are costly, leading to situations where hospitals could only afford a limited number, resulting in lower-risk patients occupying valuable resources while higher-risk patients awaited monitoring.

A team from MIT, now including Duke University computer scientist Cynthia Rudin, embarked on a mission to create an effective predictive tool. Collaborating with neurologists, they analyzed extensive data from thousands of patients using artificial intelligence, ultimately leading to the development of a scorecard known as "2HELPS2B." This tool assigns numerical values based on patterns identified in cEEG data, enabling healthcare professionals to quickly estimate a patient's seizure probability, ranging from 5% to 95%.

Traditionally, assessing seizure risk was challenging, as many patients in critical care are often unconscious or confused, making it difficult to monitor their conditions. The new system allows for a significant reduction in the time required to evaluate brain activity, with assessments now completed in as little as 60 minutes.

The cEEG monitor collects data on a patient's brain function, which is then analyzed using the scorecard. This tool evaluates factors such as specific electrical patterns and previous seizure history to determine seizure risk. A score of zero indicates a very low likelihood of seizure, while higher scores suggest increased risk, helping healthcare providers allocate resources effectively.

A recent study from researchers at UNC Chapel Hill highlighted the benefits of the 2HELPS2B scorecard, demonstrating its efficacy in helping hospitals identify lower-risk patients. This allows for a more efficient distribution of monitoring resources without sacrificing the accuracy of seizure predictions.

One of the scorecard's advantages is its straightforward design, which requires no complex calculations--just a quick tally of small numerical values. This simplicity has contributed to its widespread adoption, with estimates suggesting that over 90% of hospitals utilizing ICU EEG services are now implementing this scorecard.

The tool's public availability, funded by taxpayer dollars, is particularly rewarding for those involved in its development. The intent is to provide a resource that can benefit all healthcare institutions, enhancing patient care through improved seizure risk assessment.

As this tool continues to gain traction in hospitals, it is expected to play a crucial role in improving the management of patients at risk for seizures, ensuring that critical resources are used where they are needed most.


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