Surge in Alcohol-Related Cancer Deaths in the U.S. Over Three Decades

Sat 24th May, 2025

A recent study highlights a significant increase in alcohol-related cancer deaths in the United States, nearly doubling from 1990 to 2021. The research indicates that the annual fatalities attributable to alcohol-related cancers rose from approximately 12,000 to over 23,000 during this period.

According to the study presented at the American Society of Clinical Oncology meeting in Chicago, men accounted for about 70% of these deaths, with over 16,500 cases reported in 2021. This alarming trend has raised concerns among health professionals regarding the lack of awareness about the link between alcohol consumption and cancer.

Lead researchers emphasize the need for heightened awareness among the public and medical community regarding this association. While the dangers of tobacco are widely recognized, the same level of recognition does not extend to alcohol, despite its classification as a carcinogen by the International Agency for Research on Cancer since 1987. Furthermore, the U.S. National Toxicology Program has labeled alcohol as a known human carcinogen since 2000.

A survey conducted in 2019 by the American Institute for Cancer Research revealed that, while 89% of Americans acknowledge the link between tobacco and cancer, only 45% are aware of the risks associated with alcohol consumption. This discrepancy highlights a significant gap in public understanding of alcohol's role as a cancer risk factor.

The study utilized data from the Global Burden of Disease database, which compiles disease information and estimates risk factors contributing to illness and mortality. Researchers examined all cancer deaths, focusing on specific types of cancer known to be influenced by alcohol consumption, including breast, liver, colon, throat, voice box, mouth, and esophageal cancers.

Among the alcohol-related cancer deaths in 2021, liver cancer was the leading cause, accounting for 7,408 fatalities, followed by colon cancer with 4,687 deaths and esophageal cancer with 3,948 deaths. Notably, the proportion of cancer deaths attributed to alcohol has escalated by nearly 50% since 1990, indicating an increasing public health concern.

Interestingly, the rise in alcohol-related cancer deaths appears to be primarily due to an increase among men, as the number of deaths among women has slightly decreased since 1990. Health experts attribute alcohol's cancer risk to its potential to damage DNA and alter hormone levels, although further research is needed to fully understand how individual biological differences may influence susceptibility to alcohol-related cancers.

The researchers hope that their findings will enhance public education regarding the impact of alcohol on cancer risk, emphasizing that this is a modifiable risk factor. Increased awareness could lead to better prevention strategies and ultimately reduce the burden of alcohol-related cancer deaths.


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