New Research Highlights the Benefits of Plant-Based Diets for Cardiovascular Health

Tue 3rd Jun, 2025

Recent studies conducted by researchers at Unity Health Toronto and the University of Toronto have demonstrated the significant advantages of the Portfolio Diet, a plant-based dietary approach, in promoting heart health and reducing the risk of cardiovascular diseases.

The first study, published in BMC Medicine, assessed data from nearly 15,000 American adults and revealed that adherence to the Portfolio Diet correlates with a substantial decrease in the risk of mortality from cardiovascular disease, coronary heart disease, and overall causes of death. This is the first research to establish a connection between this diet--developed in 2003 by Professor David Jenkins--with decreased cardiovascular disease mortality.

Research indicates that even modest dietary changes, such as incorporating small amounts of nuts or beans, can yield health benefits. Participants who followed the Portfolio Diet closely had improved risk factors related to blood lipids, inflammation, and blood sugar levels, resulting in a 16% lower risk of cardiovascular disease, an 18% reduction in coronary heart disease risk, and a 14% decrease in all-cause mortality.

Moreover, even a moderate adherence to the diet was linked with a 12% reduction in cardiovascular disease risk and a 14% decrease in coronary heart disease risk factors.

The research was led by John Sievenpiper, a physician and scientist at St. Michael's Hospital, Unity Health Toronto. The study utilized data from the U.S. National Health and Nutrition Examination Survey, focusing on populations previously underrepresented in Portfolio Diet research. Researchers analyzed dietary habits through a 24-hour dietary recall survey and food frequency questionnaires.

Notably, the second study, published in BMC Public Health, shifted focus to younger individuals, investigating approximately 1,500 ethnically diverse individuals in their 20s. This research sought to understand how dietary patterns impact younger populations, which are often overlooked in similar studies.

Even among this generally healthy group, adherence to the Portfolio Diet was associated with lower levels of LDL cholesterol and other cardiovascular risk factors, indicating that adopting such dietary habits early can contribute to long-term heart health.

Researchers discovered that adhering to 50% of the Portfolio Diet in young adulthood could potentially delay the onset of cardiovascular disease by an estimated six years, while full adherence may extend this delay by up to 13 years.

The findings emphasize the importance of dietary interventions during young adulthood, a time when life transitions often lead to poorer dietary choices. The study highlights that some components of the Portfolio Diet, such as nuts and fruits, are convenient and readily accessible, making them easier for young adults to incorporate into their daily routines.


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