New Osteoporosis Treatment Recommendations for Those Over 80

Sun 13th Jul, 2025

A recent study presented at the Endocrine Society's annual meeting, ENDO 2025, emphasizes the importance of considering osteoporosis treatment for individuals over the age of 80 after experiencing a fracture. The research highlights a growing need for effective management of osteoporosis as the global population continues to age.

Osteoporosis is a condition characterized by weakened bones, making fractures more likely and often leading to severe health complications. Dr. Gianina Flocco, a resident at the Cleveland Clinic, noted that the rising prevalence of osteoporosis necessitates timely intervention to mitigate associated risks such as hospitalization and mortality.

The study analyzed data from the TriNextX health research database, focusing on 88,676 patients aged 80 and above who had sustained fractures linked to osteoporosis. The participants were divided into two groups: one receiving treatment with medications such as bisphosphonates, denosumab, raloxifene, or teriparatide, and the other group not receiving any osteoporosis therapies.

Following a five-year monitoring period post-fracture, findings revealed that patients who received treatment had a significantly lower rate of hospitalization and all-cause mortality compared to those who did not receive treatment. This underscores the necessity of proactive osteoporosis management in older adults, as untreated osteoporosis can lead to debilitating fractures and subsequent health deterioration.

As populations age, the burden of osteoporosis is expected to increase, making it imperative to address the health needs of older adults effectively. The results of this study advocate for personalized treatment approaches, particularly for those most susceptible to fractures as they age. Implementing osteoporosis treatment for elderly patients could play a vital role in enhancing their quality of life and prolonging their health span.

In summary, the study supports the recommendation to initiate osteoporosis treatment in individuals over 80 to reduce the risk of fractures and their associated complications. By focusing on this vulnerable demographic, healthcare providers can significantly improve health outcomes and quality of life for the aging population.


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