Innovative Treatment Shows Promise in Enhancing Post-Stroke Speech Recovery

Thu 17th Apr, 2025

A recent study conducted by researchers at the University of Calgary has unveiled encouraging results regarding the improvement of speech after a stroke. This groundbreaking research, which involved 44 participants, focuses on the use of transcranial magnetic stimulation (TMS) in conjunction with intensive speech therapy to aid those suffering from post-stroke aphasia.

Aphasia, a condition that impairs an individual's ability to communicate and formulate words, affects many stroke survivors. One participant, Lucy Mulloor, experienced a massive stroke that left her unable to speak or move the right side of her body. After five months in the hospital, she sought a solution to regain her speech capabilities and enrolled in the study led by Dr. Sean Dukelow.

Dr. Dukelow, a professor at the Cumming School of Medicine, expressed excitement over the study's results. The research aimed to explore whether the brain could continue to recover and repair itself long after a stroke, especially in individuals already six months post-event. The findings suggest that it can, providing hope for many stroke survivors.

The trial was meticulously designed as a double-blind, sham-controlled randomized study, meaning that neither the participants nor the researchers knew who was receiving the actual treatment and who was part of the control group. All participants underwent two weeks of intensive speech therapy, but only one group received active TMS treatment, while the other group received a sham procedure that did not stimulate the brain.

Following the treatment period, participants engaged in extensive repetitive drills as part of the multimodality aphasia therapy (M-MAT), which incorporated various activities such as reading, writing, and drawing to enhance speech functionality. The lead speech-language pathologist, Shannan Love, noted that many participants demonstrated significant functional improvements during the trials.

Beyond measurable speech gains, participants also reported enhanced confidence and mood, and some even observed increased movement in their arms and hands. This holistic approach to recovery showcases the potential benefits of combining various therapeutic methods.

Trevor Low, a doctoral student involved in the research, highlighted that all participants showed some level of speech improvement, with the group receiving TMS exhibiting notably significant gains. This indicates that the brain's capacity for rewiring and recovery remains intact long after a stroke.

Mulloor, who was three years post-stroke at the time of her participation, noted a remarkable improvement in her ability to recall words and engage in conversation with newfound confidence. The researchers confirmed that she was part of the TMS group, illustrating the tangible benefits of the treatment.

The study's findings were published in the journal Neurology, offering valuable insights into the ongoing recovery possibilities for stroke survivors dealing with aphasia. As research in this field continues to evolve, it may pave the way for more effective treatments and rehabilitation strategies for individuals affected by strokes.


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