New Study Indicates Potential Benefits of Caloric Restriction on Mental Health

Tue 20th May, 2025

Recent research has provided preliminary insights into the relationship between dietary habits and mental health, particularly regarding depressive symptoms. A systematic review and meta-analysis conducted by researchers at Bond University in Queensland examined the impact of various dietary interventions on depression and anxiety in adults. The findings, published in the Annals of Internal Medicine, suggest that calorie-restrictive and low-fat diets may offer some reduction in depressive symptoms for individuals with high cardiometabolic risk, although the evidence remains inconclusive.

The study analyzed data from 25 randomized controlled trials (RCTs) that included over 57,000 adult participants. These trials evaluated the effects of dietary changes--specifically calorie restriction, low-fat diets, and Mediterranean-style diets--on mental health over a minimum duration of three months. The primary focus was to assess changes in the severity of depression and anxiety, with secondary outcomes measuring the incidence of these conditions and overall quality of life (QoL).

Results indicated that compared to standard dietary practices, both calorie-restricted and low-fat diets might alleviate depressive symptoms among adults who are at increased risk for cardiometabolic issues. However, the influence of these diets on anxiety levels remains unclear. The study also explored the effects of low-fat diets in comparison to other dietary approaches, finding some indication that they may help lower anxiety, yet their efficacy in reducing depression is less certain.

Additionally, the evidence surrounding the Mediterranean diet in relation to depression, anxiety, and QoL was found to be insufficient, suggesting that further research is needed to clarify these associations.

Despite the potential benefits identified for specific dietary interventions, the researchers emphasized the need for caution. They highlighted the low confidence in the findings and advised individuals considering dietary changes for mental health reasons to consult healthcare professionals beforehand. The study underscores the necessity for continued exploration into how dietary modifications might serve as complementary strategies alongside conventional treatments for depression and anxiety.

This research adds to the growing body of literature that seeks to understand the complex interplay between diet and mental health, paving the way for future studies to further investigate the nuances of dietary impact on psychological well-being.


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