Seven Confirmed Dead, Multiple Injured Following UPS Cargo Plane Crash in Louisville

Wed 5th Nov, 2025

A UPS cargo aircraft crashed shortly after takeoff at Louisville's Muhammad Ali International Airport, resulting in at least seven fatalities and 11 injuries, according to authorities. The incident, which occurred as the plane was departing for Honolulu, led to a substantial fire and significant damage near the airport's runway.

The Federal Aviation Administration reported that the crash took place at approximately 5:15 p.m. The aircraft involved was a McDonnell Douglas MD-11, built in 1991. Video evidence from the scene showed fire emerging from the plane's left wing before it attempted to ascend, ultimately crashing and igniting a large explosion. Debris from a nearby building was visible, indicating the intensity of the impact.

Officials confirmed that among the seven who lost their lives, four were not on the aircraft at the time. The injured individuals suffered a range of injuries, some described as severe. Emergency response teams were immediately dispatched to manage the aftermath and provide aid to those affected.

The airport's main operations, including UPS's Worldport package sorting facility, were suspended following the crash. The facility, a critical logistics hub, usually processes over 400,000 packages per hour and employs thousands of workers. There was no immediate information regarding when normal activities would resume.

Authorities indicated that multiple businesses near the crash site sustained damage, notably Kentucky Petroleum Recycling and an adjacent auto parts company. Community members gathered at a local police academy seeking information about friends and relatives who may have been in the affected area at the time of the incident.

Eyewitness accounts described hearing a powerful explosion and observing extensive flames and smoke rising from the scene. Residents and workers in the vicinity reported feeling the ground shake, with some likening the aftermath to a disaster zone. The psychological impact on the local population was evident as many sought reassurance regarding the safety of their loved ones.

Aviation experts reviewing the available footage noted that the aircraft appeared to struggle with lift as a fire blazed near one of its engines. Given the significant quantity of fuel typically carried by cargo planes, the risk of a rapid escalation of the fire was considerable, contributing to the severity of the explosion.

The National Transportation Safety Board (NTSB) has assumed control of the investigation, deploying a team to analyze the cause of the crash. The airport remained closed to all flights, with authorities stating that operations would not resume until the area was deemed safe.

The Louisville Metropolitan Police Department and other emergency services continued to secure the site and coordinate with federal investigators. Officials did not provide an expected timeline for reopening the airport, citing the complexity and danger of the scene.

The crash occurred in an area close to residential neighborhoods, commercial businesses, and recreational facilities, raising concerns about the broader impact on the community. Local government leaders expressed their condolences to those affected and emphasized their commitment to supporting the ongoing investigation and recovery efforts.

Further updates are anticipated as authorities gather additional information and work to determine the factors that led to the fatal crash.


More Quick Read Articles »