Study Reveals No Adverse Effects of Puberty Blockers on Sexual Function in Transgender Adults

Wed 18th Jun, 2025

Recent research conducted by Amsterdam University Medical Centers has found that puberty blockers do not adversely affect sexual functioning in transgender adults. This finding is significant given the ongoing discussions surrounding the use of puberty blockers for transgender youth.

Puberty blockers are medications that temporarily halt the physical changes associated with puberty, allowing young individuals to explore their gender identity without the distress of unwanted physical changes. While previous studies have established the mental health benefits of these blockers, little was known about their long-term effects on sexual satisfaction and functioning.

In this study, researchers surveyed 70 transgender adults who had initially used puberty blockers before transitioning to gender-affirming hormones. The survey aimed to assess their sexual experiences, satisfaction levels, and any difficulties they encountered related to sexual functioning, with participants responding approximately 14 years after beginning treatment.

The findings, published in the Journal of Sexual Medicine & Research, indicated that over half of the trans men and approximately 40% of trans women reported satisfaction with their sex lives, comparable to the sexual satisfaction levels found in the cisgender population. Furthermore, the study revealed no significant differences in sexual satisfaction between those who began taking puberty blockers early or later in their puberty.

Most participants reported no issues with desire, arousal, or achieving orgasm. Among the sexual problems identified, trans men frequently mentioned challenges in initiating sexual activity, while trans women often reported difficulties reaching orgasm. However, these issues were generally not perceived as highly stressful.

These results not only provide valuable insights for healthcare providers but also help alleviate concerns that transgender youth and their families may have regarding sexual functioning in the future. The lead researcher emphasized the importance of informing young people about what to expect sexually after starting puberty blockers.

In addition, the researchers highlighted the complexity of sexual experiences, which are influenced by various physical and psychosocial factors. For instance, the challenge of seeking and initiating sexual contact often arose in the discussions, suggesting that these concerns are not solely linked to the physical effects of hormone therapy.

This study contributes to a growing body of research that aims to support transgender youth in their journey by providing them with accurate information regarding the implications of puberty blockers on their future sexual health.


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