Oropouche Virus More Prevalent Than Previously Thought

Tue 15th Apr, 2025

The Oropouche virus is proving to be significantly more widespread in Latin America than previously estimated. Recent research conducted across Bolivia, Colombia, Costa Rica, Ecuador, and Peru indicates that approximately 6.3% of nearly 9,420 blood samples tested positive for antibodies against the virus. This suggests that at least one in every 16 individuals in these regions has encountered this infection at some point in their lives, according to an expert involved in the study.

There are pronounced regional variations in antibody prevalence. As detailed in the international study published in the journal The Lancet Infectious Diseases, Costa Rica showed about 2% of the samples with antibodies, while Ecuador reported around 5%. Notably, in the Amazon regions, the prevalence exceeded 10%. The blood samples analyzed were collected between 2001 and 2022.

In Germany, the Robert Koch Institute (RKI) has reported four cases of Oropouche fever, three of which occurred in 2024 and one in the current year. All reported cases involved travelers returning from Central and South America, and no local transmission of the virus has been observed in Germany.

Symptoms associated with the Oropouche virus (OROV) are similar to those of dengue and chikungunya fevers, including headaches, muscular and joint pain, nausea, diarrhea, and sometimes skin rashes. Although severe cases are rare, there are indications that the virus could potentially harm unborn children. Currently, there is no specific treatment or vaccine available for this virus.

First identified in the 1950s, the Oropouche virus is transmitted in Latin America by various mosquito species. Historically, only a few cases were documented annually due to limited testing. However, since late 2023, the annual number of infections has surged to over 20,000, with the reasons for this increase remaining unclear. Researchers suggest that climatic factors, including rainfall and temperature, may significantly influence the virus's spread. The heavy rainfall experienced in parts of South America last year may have contributed to larger mosquito populations, facilitating the virus's transmission.

Overall, the findings highlight the urgent need for increased awareness and testing for the Oropouche virus as it continues to pose a public health challenge in the region.


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