New Research Highlights Risks of Unsupervised Vitamin Supplementation in Cancer Care

Tue 13th May, 2025

A recent investigation led by a team of experts from the Sbarro Health Research Organization (SHRO) has raised significant concerns regarding the use of vitamin supplements in cancer prevention and treatment. The study, published in the Expert Review of Anticancer Therapy, scrutinizes the prevalent belief that over-the-counter vitamins and trendy diets can independently enhance life expectancy or improve cancer outcomes.

Dr. Salvatore Cortellino and Professor Antonio Giordano, both affiliated with SHRO and renowned for their work in the field of molecular oncology, emphasize that while vitamin deficiencies are common among cancer patients and can elevate cancer risk, the supplementation of vitamins through pharmaceutical-grade products has not proven to deliver clear clinical benefits.

Instead of relying on supplements, the authors advocate for a balanced diet, particularly highlighting the Mediterranean diet as a reliable means of ensuring adequate micronutrient intake. The review also expresses concerns about hypervitaminosis, a condition that arises from excessive vitamin consumption without proper medical guidance. Such imbalances could inadvertently promote tumor progression in cancer patients.

The study critically evaluates popular dietary trends, including ketogenic diets, intermittent fasting, and strict veganism. Although some of these diets have garnered support from preclinical studies, they lack substantial evidence for their effectiveness in treating cancer in humans. Furthermore, restrictive dietary practices can potentially worsen cancer-related cachexia or lead to malnutrition, especially in vulnerable populations such as the elderly.

Professor Giordano cautions that unmonitored adherence to dietary trends can be detrimental to cancer patients, asserting the importance of evidence-based medicine and a personalized nutritional approach. The authors advise patients to seek professional medical advice before making significant alterations to their diet, especially if they have existing risk factors or are actively battling the disease.

The study concludes by reiterating that optimal health is maintained through physiological balance, achieved by a wholesome diet, adequate caloric intake, and regular physical activity tailored to individual requirements. These principles align with the European Code Against Cancer and the Mediterranean lifestyle, which serve as foundational strategies for cancer prevention and overall well-being.


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