Long-term Air Pollution Exposure May Deteriorate Cognitive Health in Seniors

Mon 7th Apr, 2025

Recent findings from University College London indicate that prolonged exposure to elevated levels of air pollution could adversely affect cognitive health in older adults residing in England. The research, published in The Journals of Gerontology, Series A, highlights a significant correlation between high concentrations of nitrogen dioxide (NO2) and fine particulate matter (PM2.5) and declines in essential cognitive functions, particularly in language abilities.

Nitrogen dioxide, a common pollutant, primarily enters the atmosphere through the burning of fossil fuels, including emissions from vehicles, power plants, and various machinery. PM2.5, which consists of minuscule particles that can penetrate deep into the lungs, often arises from the combustion of gasoline, diesel, oil, or wood.

The study analyzed data from 1,127 participants aged 65 and above who were involved in the English Longitudinal Study of Ageing's Harmonized Cognitive Assessment Protocol (ELSA-HCAP) in 2018. Over an eight to ten-year period from 2008 to 2017, the researchers assessed participants' exposure to air pollution and evaluated their memory, executive functions--such as problem-solving and adaptability--and overall cognitive performance through various established memory assessments.

The results revealed that individuals living in regions with the highest pollution levels performed significantly worse on cognitive assessments compared to those in areas with average pollution. The most notable deficits were observed in language skills, with participants in the most polluted areas scoring in the lowest third on cognitive evaluations.

Additionally, the study noted that different pollution sources had distinct impacts on cognitive health. For instance, pollutants from industrial activities, home heating, and fuel combustion were strongly associated with poor language performance, specifically regarding the speed of word retrieval.

While the research did not delve into the mechanisms behind these associations, it posits that increased exposure to specific air pollutants may be linked to impairments in the temporal lobe, a brain region vital for language processing and fluency. Further investigation is necessary to elucidate these connections.

Researchers emphasize the necessity for policymakers to enhance air quality regulations, particularly in areas where pollution levels are still high, to safeguard cognitive health as populations age. A deputy director of the ELSA study remarked that tracking pollution levels over a decade has provided compelling evidence that sustained exposure to these pollutants can harm brain function.

However, the study does have limitations, including the air pollution data covering only a decade, which may not accurately reflect lifetime exposure. The reliance on yearly averages may overlook the effects of short-term spikes in pollution, and the study's sample size and geographic focus on England may not represent broader trends.


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