Increased Fish Consumption May Slow Disability Progression in Multiple Sclerosis

Recent research suggests that a higher intake of fish may be linked to a slower progression of disability in individuals with multiple sclerosis (MS). A study published in the Journal of Neurology, Neurosurgery & Psychiatry examined data from a significant cohort of participants to explore the relationship between fish consumption and disability outcomes in MS patients.

The research team, led by scientists at the Karolinska Institute in Stockholm, analyzed data from 2,719 participants enrolled in the Epidemiological Investigation of MS. This population-based case-control study assessed fish intake alongside results from the Expanded Disability Status Scale (EDSS). Participants were categorized based on their fish consumption at the time of diagnosis and were followed for up to 15 years. Additionally, a digital follow-up questionnaire was conducted in 2021 to evaluate changes in fish consumption over time among 1,719 participants.

The findings indicated that participants with higher overall consumption of both lean and oily fish at diagnosis had a significantly reduced risk of confirmed disability worsening over a period of 24 weeks. Specifically, the hazard ratios were noted as 0.66 for general disability progression, and even lower for more severe disability levels (EDSS3 and EDSS4), with ratios of 0.55 and 0.57, respectively. These associations remained significant even after adjusting for various lifestyle factors. Furthermore, patients who consistently maintained a high fish intake during the follow-up period exhibited more pronounced protective effects against disability progression.

The authors of the study propose that the beneficial effects of fish consumption may stem from the anti-inflammatory and neuroprotective properties of essential nutrients found in fish. They emphasize the importance of dietary choices in the management of multiple sclerosis, suggesting that incorporating fish into the diet could play a role in slowing the progression of this debilitating disease.

While one of the researchers disclosed links to the pharmaceutical industry, the study itself provides a compelling perspective on the potential benefits of dietary habits for individuals living with MS.