Cycling Linked to Improved Brain Health in Aging Adults

Mon 16th Jun, 2025

Recent research suggests that regular cycling may contribute significantly to healthier brain aging, potentially lowering the risk of dementia and Alzheimer's disease. A study published in JAMA Network Open indicates that individuals who bike for transportation exhibit a 19% reduced risk of developing dementia and a 22% reduced risk of Alzheimer's compared to those who do not cycle.

The study highlights that cycling might also enhance the size of the hippocampus, a brain region critical for memory. Experts in geriatric health emphasize that cycling involves moderate to high-intensity exercise, which requires more complex brain functions than walking, thus potentially offering greater benefits in reducing dementia risk.

In this comprehensive study, researchers evaluated data from nearly 480,000 participants in the UK Biobank, a long-term health study focusing on individuals from England, Scotland, and Wales. Participants reported their primary modes of transportation, excluding commutes to work.

During an average follow-up period of 13 years, over 8,800 participants were diagnosed with dementia, and nearly 4,000 were diagnosed with Alzheimer's. Findings revealed a significant decrease in the risk of these cognitive disorders among those who either cycled or included cycling as part of a broader active travel lifestyle that encompasses walking, driving, or using public transport.

The research team, led by an associate professor at Tongji Medical College, concluded that promoting cycling and other forms of active travel could yield substantial public health benefits, particularly for cognitive health in middle-aged and older adults. The study also revealed that individuals without the APOE E4 genetic variant, a known risk factor for Alzheimer's, experienced a 26% lower risk of dementia and a 25% lower risk of Alzheimer's when they engaged in cycling. Conversely, the protective benefits of cycling were less pronounced for those carrying the APOE E4 variant.

Interestingly, the study found that driving may offer some protective effects against dementia compared to using public transportation, suggesting that even less active forms of travel can contribute positively to brain health.

While the observational nature of this study does not allow for definitive cause-and-effect conclusions, experts recommend that engaging in any outdoor activity can be beneficial for reducing dementia risk. They advocate for cycling when possible, but if that is not feasible, walking is also encouraged as a healthy alternative.

Overall, this study underscores the importance of incorporating physical activity into daily routines, particularly through active travel modes like cycling, to enhance cognitive health and promote brain aging.


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