Critical Review Highlights Deficiencies in Newborn Pain Assessment Scales

Mon 14th Apr, 2025

A recent review published in the Cochrane Database of Systematic Reviews has identified significant deficiencies in the clinical rating scales currently used to assess pain in newborns. This review underscores the pressing need for enhanced tools and international cooperation in the assessment of neonatal pain.

Accurate pain measurement is vital for newborns, yet the review reveals that none of the existing scales are supported by the robust evidence and methodological rigor necessary to establish their validity and reliability in clinical settings. Neonatal pain assessment and management present considerable challenges for healthcare professionals globally, with over 40 different rating scales developed and adapted to evaluate various pain parameters.

Approximately 6% to 9% of all newborns are admitted to neonatal intensive care units (NICUs) due to health issues or prematurity, where they undergo multiple painful procedures daily. Such experiences can have long-term adverse effects on these infants, making effective pain assessment tools essential.

The Cochrane review analyzed 79 studies involving over 7,000 infants across 26 countries, evaluating 27 distinct clinical rating scales. The findings indicated that all reviewed scales were backed by very low-quality evidence, pointing to significant limitations in their effectiveness and clinical relevance. Over 70% of the scales did not sufficiently evaluate content and structural validity, both crucial factors for selecting a measurement tool. Without a solid foundation in these areas, other essential measures, such as reliability, cannot be assessed accurately.

Assessing pain in newborns is inherently more complex than in adults, with existing limitations leading to potential over- or under-estimation of pain levels. This can result in either unnecessary sedation or inadequate pain management, which may jeopardize the safety of infants through side effects such as withdrawal symptoms or prolonged discomfort. Premature infants are particularly challenging, as their immature condition often limits their ability to display clear pain behaviors.

Given the uncertainties highlighted in the review, healthcare professionals are urged to exercise caution and not overly rely on the existing rating scales. Instead, there should be a concerted effort to minimize painful procedures for these vulnerable patients.

Despite the concerning results of this review, it also presents an opportunity for advancement in neonatal pain assessment through global collaboration and innovation. Experts see this as a call to action for clinicians and researchers to come together to develop a rigorously validated pain assessment scale from the ground up, ensuring that all necessary validation checks are met before implementation in clinical practice.

Such collaborative efforts could significantly enhance the quality of pain management for newborns worldwide, ultimately improving their health outcomes.


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