Early Detection Saves Kidneys and Lives

Increasing attention towards kidney health could prevent or slow the progression of chronic kidney disease (CKD). Recent discussions at an online press conference held by the German Society of Nephrology (DGfN) highlighted the silent nature of CKD, which often goes unnoticed until it significantly impacts health.

CKD does not typically present any pain or immediate symptoms, but it is known to contribute to atherosclerosis, cardiovascular diseases, and a higher mortality rate. Professor Dr. Julia Weinmann-Menke from Mainz University Hospital, who serves as the spokesperson for the DGfN, emphasized that the risk for heart attacks, strokes, and other cardiovascular complications increases even in the early stages of CKD.

Diabetes and hypertension are two of the most common causes of CKD. Persistent high blood sugar levels lead to vascular changes, particularly damaging the small blood vessels in the kidneys, resulting in diabetic nephropathy, which is the leading cause of dialysis dependency in Germany. Similarly, chronic high blood pressure can harden and narrow renal capillaries, leading to inadequate blood flow, kidney tissue damage, and reduced filtration capacity. This creates a vicious cycle where worsening kidney function often results in elevated blood pressure.

To effectively combat this issue, the DGfN advocates for targeted screening among at-risk individuals. Regular monitoring of kidney function through tests measuring the estimated glomerular filtration rate (eGFR) and the urine albumin-to-creatinine ratio (UACR) is essential. However, recent studies indicate that fewer than half of at-risk patients receive kidney function assessments during routine visits to their general practitioners, and less than one percent have their UACR evaluated.

Weinmann-Menke urges that these kidney health indicators be incorporated into the standard health check-ups available to individuals over 35, which is currently not the case. She advises patients with obesity, diabetes, hypertension, cardiovascular diseases, or a family history of kidney issues to proactively request their creatinine levels, eGFR, and albuminuria tests from their healthcare providers.

By enhancing awareness and encouraging regular kidney function evaluations, there is potential to significantly improve patient outcomes and quality of life, ultimately saving both kidneys and lives.